Center for Clinical Genetics
Pregnancy Screening Lab (PSL)
The Pregnancy Screening Laboratory (PSL) offers state-of-the-art testing for identifying pregnancies at increased risk for chromosome conditions such as Down syndrome (trisomy 21) or trisomy 18, or open neural tube defects, such as spina bifida or anencephaly.
The PSL offers screening tests in both the first and second trimester of pregnancy.
Our experienced staff takes great care in interpreting the results of testing and communicating these results to the referring physician. In the event of a positive screening test (increased risk), our genetic counselors are available to discuss with the parents the decision to have further testing.
This decision should be based on a number of factors, including the risk of birth defects and the risks of the procedure.
The PSL performs the following testing ( view PSL specimen handling instructions) :
- First-trimester screening (PAPP-A, hCG, nuchal translucenc
- Quad screen (AFP, hCG, uE3, Inhibin-A) Amniotic fluid AFP
- Amniotic fluid AchE